I've been trying to run World of Warcraft 5.4 (Cataclysm/Mists of Pandaria trial) on my Ubuntu desktop "dop". Although it has Platinum status on wine, I still have some issues with it.
I haven't played in quite some years, but I did used to play on Ubuntu and I mainly had sound issues. I have upgraded my hardware since, and I can say sounds works and graphics perform surprisingly well with my CPU's integrated graphics (Intel Core i7 4770S "Haswell" with Intel HD 4600 GT2). I have about 50fps just running around with medium settings on 1920x1080.
To get to this point:
Sound wasn't working at this point so I referred back to the Ubuntu help article on WoW. Under "audio" it is suggested to look in the winecfg under the Audio tab, but there was not even a driver selected in my case. It is also mentioned that it might be caused by an old wine installation. This was definitely possible, because I copied my home dir from my old installation. So I followed this instruction to delete the Audio entry inside the [HKEY_CURRENT_USER\Software\Wine\Drivers] registry key with regedit. Now the winealsa.drv driver was available in winecfg and sound works fine in the game.
I also had the problem that my secondary monitor would turn off when starting the game and I had to do this:
What's still not working is updating. It might be my own doing by copying my Windows installation to prevent the huge download a second time. I can start the launcher/updater, but it will just hang and log something about nog being able to write to a system directory. I have solved it so far by just copying my Windows installation again after an update (or at least the modified files).